Director: Conrad Vernon
When Susan Murphy is unwittingly clobbered by a meteor full of outer space gunk on her wedding day, she mysteriously grows to 49-feet-11-inches. The military jumps into action and captures Susan, secreting her away to a covert government compound. She is renamed Ginormica and placed in confinement with a ragtag group of Monsters...
Reese Witherspoon
Susan Murphy / Ginormica (voice)
Seth Rogen
B.O.B. (voice)
Hugh Laurie
Dr. Cockroach Ph.D. (voice)
Rainn Wilson
Gallaxhar (voice)
Will Arnett
The Missing Link (voice)
Kiefer Sutherland
General W.R. Monger (voice)
Paul Rudd
Derek Dietl (voice)
Stephen Colbert
President Hathaway (voice)
Julie White
Wendy Murphy (voice)
Jeffrey Tambor
Carl Murphy (voice)
Amy Poehler
Computer (voice)
Ed Helms
News Reporter (voice)
Renée Zellweger
Katie (voice)
Sean Bishop
Private Bullhorn / Helicopter Pilot / Advisor Ortega (voice)
Rich Dietl
Commander / Advisor Smith (voice)
Rob Letterman
Secret Service Man #1 / Lieutenant (voice)
Tom McGrath
Wilson (voice)
Chris Miller
Advisor Cole / Army Commander Jones (voice)
Mike Mitchell
Advisor Wedgie (voice)
Kent Osborne
Technician Jerry (voice)
Reese Witherspoon
Susan Murphy / Ginormica (voice)
Seth Rogen
B.O.B. (voice)
Hugh Laurie
Dr. Cockroach Ph.D. (voice)
Rainn Wilson
Gallaxhar (voice)
Will Arnett
The Missing Link (voice)
Kiefer Sutherland
General W.R. Monger (voice)
Paul Rudd
Derek Dietl (voice)
Stephen Colbert
President Hathaway (voice)
Julie White
Wendy Murphy (voice)
Jeffrey Tambor
Carl Murphy (voice)
Amy Poehler
Computer (voice)
Ed Helms
News Reporter (voice)
Renée Zellweger
Katie (voice)
Sean Bishop
Private Bullhorn / Helicopter Pilot / Advisor Ortega (voice)
Rich Dietl
Commander / Advisor Smith (voice)
Rob Letterman
Secret Service Man #1 / Lieutenant (voice)
Tom McGrath
Wilson (voice)
Chris Miller
Advisor Cole / Army Commander Jones (voice)
Mike Mitchell
Advisor Wedgie (voice)
Kent Osborne
Technician Jerry (voice)
Reese Witherspoon
Susan Murphy / Ginormica (voice)
Seth Rogen
B.O.B. (voice)
Hugh Laurie
Dr. Cockroach Ph.D. (voice)
Rainn Wilson
Gallaxhar (voice)
Will Arnett
The Missing Link (voice)
Kiefer Sutherland
General W.R. Monger (voice)
Paul Rudd
Derek Dietl (voice)
Stephen Colbert
President Hathaway (voice)
Julie White
Wendy Murphy (voice)
Jeffrey Tambor
Carl Murphy (voice)
Amy Poehler
Computer (voice)
Ed Helms
News Reporter (voice)
Renée Zellweger
Katie (voice)
Sean Bishop
Private Bullhorn / Helicopter Pilot / Advisor Ortega (voice)
Rich Dietl
Commander / Advisor Smith (voice)
Rob Letterman
Secret Service Man #1 / Lieutenant (voice)
Tom McGrath
Wilson (voice)
Chris Miller
Advisor Cole / Army Commander Jones (voice)
Mike Mitchell
Advisor Wedgie (voice)
Kent Osborne
Technician Jerry (voice)